[13] Leyton Orient 0-1 Newport County [5] 2022-01-25 19:45
Stadion: Matchroom Stadium Round: 24
Schiedsrichter: James Bell Home Manager: Kenny Jackett Away Manager: James Rowberry
Head to Head
| England - League 2 | 2021/09/04 14:00 | Newport County v Leyton Orient | D | 2-2 |
| England - League 2 | 2021/03/20 13:00 | Newport County v Leyton Orient | W | 0-1 |
| England - League 2 | 2020/12/12 15:00 | Leyton Orient v Newport County | W | 2-1 |
| England - FA Cup | 2020/11/07 15:00 | Leyton Orient v Newport County | L | 1-2 |
| England - League 2 | 2020/01/25 15:00 | Leyton Orient v Newport County | W | 2-1 |
| England - League 2 | 2019/12/29 15:00 | Newport County v Leyton Orient | D | 1-1 |
| England - League 2 | 2017/03/04 15:00 | Newport County v Leyton Orient | W | 0-4 |
| England - League 2 | 2016/08/13 14:00 | Leyton Orient v Newport County | L | 0-1 |
Home History
| England - League 2 | 2022/01/22 15:00 | Leyton Orient v Port Vale | D | 0-0 |
| England - FA Cup | 2022/01/09 14:00 | Stoke v Leyton Orient | L | 2-0 |
| England - League 2 | 2021/12/18 15:00 | Tranmere v Leyton Orient | L | 1-0 |
| England - League 2 | 2021/12/11 15:00 | Leyton Orient v Crawley Town | L | 1-2 |
| England - League 2 | 2021/12/07 19:45 | Leyton Orient v Swindon | W | 4-1 |
| England - FA Cup | 2021/12/04 15:00 | Leyton Orient v Tranmere | W | 4-0 |
| England - EFL Trophy | 2021/11/30 19:00 | Leyton Orient v Milton Keynes Dons | L | 4-5 |
| England - League 2 | 2021/11/27 15:00 | Northampton v Leyton Orient | L | 1-0 |
Away History
| England - League 2 | 2022/01/22 15:00 | Scunthorpe v Newport County | W | 0-1 |
| England - League 2 | 2022/01/15 12:30 | Newport County v Harrogate Town | W | 4-0 |
| England - League 2 | 2022/01/08 15:00 | Newport County v Salford City | L | 0-2 |
| England - League 2 | 2022/01/01 15:00 | Walsall v Newport County | D | 3-3 |
| England - League 2 | 2021/12/18 15:00 | Rochdale v Newport County | L | 3-0 |
| England - League 2 | 2021/12/11 15:00 | Newport County v Port Vale | W | 2-1 |
| England - League 2 | 2021/12/07 19:45 | Newport County v Sutton Utd | W | 3-2 |
| England - League 2 | 2021/11/26 19:45 | Colchester v Newport County | D | 1-1 |