| NCAAF | 11/11 18:30 | 1 | Otterbein Cardinals v John Carroll Blue Streaks | L | 22-37 | |
| NCAAF | 11/04 17:30 | 1 | Ohio Northern Polar Bears v Otterbein Cardinals | L | 49-6 | |
| NCAAF | 10/28 17:30 | 1 | Mount Union v Otterbein Cardinals | L | 51-14 | |
| NCAAF | 10/21 16:30 | 1 | Otterbein Cardinals v Baldwin Wallace Yellow Jackets | L | 0-24 | |
| NCAAF | 10/14 21:00 | 1 | Heidelberg Student Princes v Otterbein Cardinals | L | 28-8 | |
| NCAAF | 09/30 17:30 | 1 | Capital Crusaders v Otterbein Cardinals | L | 35-31 | |
| NCAAF | 09/23 17:30 | 1 | Marietta Pioneers v Otterbein Cardinals | L | 50-0 | |
| NCAAF | 09/16 19:00 | 1 | Otterbein Cardinals v Wilmington Quakers | L | 21-47 | |
| NCAAF | 09/09 16:00 | 1 | Otterbein Cardinals v Muskingum Muskies | L | 14-27 | |
| NCAAF | 09/02 16:00 | 1 | Otterbein Cardinals v Ohio Wesleyan Battling Bishops | L | 21-35 | |
| NCAAF | 11/12 18:30 | 1 | John Carroll Blue Streaks v Otterbein Cardinals | L | 62-7 | |
| NCAAF | 11/05 17:30 | 1 | Otterbein Cardinals v Ohio Northern Polar Bears | L | 7-42 |