[8] Tijuana 0-2 Santos Laguna [5] 2022-08-26 02:05
Stadion: Estadio Caliente Round: 16
Schiedsrichter: Adonai Escobedo Gonzalez Home Manager: Ricardo Valino Away Manager: Eduardo Fentanes
Head to Head
| Mexiko - Liga MX | 2022/03/14 01:00 | Santos Laguna v Tijuana | L | 4-0 |
| Mexiko - Liga MX | 2021/09/11 02:06 | Tijuana v Santos Laguna | W | 2-1 |
| Mexiko - Liga MX | 2021/03/14 03:05 | Tijuana v Santos Laguna | L | 0-1 |
| Mexiko - Liga MX | 2020/10/12 00:06 | Santos Laguna v Tijuana | L | 2-0 |
| Mexiko - Liga MX | 2020/01/11 03:10 | Tijuana v Santos Laguna | W | 2-1 |
| Mexiko - Liga MX | 2019/10/19 02:06 | Santos Laguna v Tijuana | L | 4-1 |
| Mexiko - Liga MX | 2019/02/11 00:00 | Santos Laguna v Tijuana | D | 1-1 |
| Mexiko - Liga MX | 2018/08/23 02:06 | Tijuana v Santos Laguna | D | 2-2 |
Home History
| Mexiko - Liga MX | 2022/08/20 22:00 | Queretaro v Tijuana | L | 2-0 |
| Mexiko - Liga MX | 2022/08/18 02:05 | Cruz Azul v Tijuana | W | 1-2 |
| Mexiko - Liga MX | 2022/08/13 02:05 | Tijuana v Puebla | D | 3-3 |
| Mexiko - Liga MX | 2022/08/07 17:00 | Toluca v Tijuana | L | 3-1 |
| Mexiko - Liga MX | 2022/07/31 02:05 | Tijuana v Mazatlan FC | W | 2-0 |
| Mexiko - Liga MX | 2022/07/27 00:00 | Atlas v Tijuana | W | 1-2 |
| Mexiko - Liga MX | 2022/07/24 01:05 | Tijuana v Club America | W | 2-0 |
| Mexiko - Liga MX | 2022/07/18 00:00 | Tigres UANL v Tijuana | L | 1-0 |
Away History
| Mexiko - Liga MX | 2022/08/21 17:00 | Unam Pumas v Santos Laguna | W | 1-5 |
| Mexiko - Liga MX | 2022/08/19 00:00 | Santos Laguna v Leon | W | 2-1 |
| Mexiko - Liga MX | 2022/08/15 00:05 | Tigres UANL v Santos Laguna | L | 2-0 |
| Mexiko - Liga MX | 2022/08/07 02:05 | Santos Laguna v Cruz Azul | W | 4-0 |
| Mexiko - Liga MX | 2022/08/01 00:05 | Santos Laguna v Atlas | W | 1-0 |
| Mexiko - Liga MX | 2022/07/23 22:00 | Toluca v Santos Laguna | L | 2-1 |
| Mexiko - Liga MX | 2022/07/17 00:05 | Santos Laguna v Chivas Guadalajara | D | 1-1 |
| Mexiko - Liga MX | 2022/07/09 02:05 | Puebla v Santos Laguna | L | 1-0 |