[5] BUF Sabres 0-5 BOS Bruins [4] 2022-04-28 23:00
Stadion: TD Garden
Home Manager: Bruce Cassidy Away Manager: Don Granato
Head to Head
| NHL | 2022/01/01 18:00 | BUF Sabres v BOS Bruins | L | 3-4 |
| NHL | 2021/11/25 00:00 | BOS Bruins v BUF Sabres | L | 5-1 |
| NHL | 2021/10/22 23:00 | BOS Bruins v BUF Sabres | L | 4-1 |
| NHL | 2021/05/01 17:00 | BUF Sabres v BOS Bruins | L | 2-6 |
| NHL | 2021/04/29 23:00 | BUF Sabres v BOS Bruins | L | 2-5 |
| NHL | 2021/04/23 23:00 | BOS Bruins v BUF Sabres | W | 4-6 |
| NHL | 2021/04/22 23:00 | BOS Bruins v BUF Sabres | L | 5-1 |
| NHL | 2021/04/20 22:30 | BOS Bruins v BUF Sabres | L | 2-0 |
| NHL | 2021/04/13 23:00 | BUF Sabres v BOS Bruins | L | 2-3 |
| NHL | 2021/03/27 17:00 | BUF Sabres v BOS Bruins | L | 2-3 |
| NHL | 2021/03/18 23:00 | BOS Bruins v BUF Sabres | L | 4-1 |
| NHL - Pre-Season | 2020/03/09 12:42 | BOS Bruins v BUF Sabres | L | 3-2 |
| NHL | 2019/12/30 00:00 | BUF Sabres v BOS Bruins | L | 2-3 |
| NHL | 2019/12/28 00:00 | BOS Bruins v BUF Sabres | L | 3-0 |
| NHL | 2019/11/22 00:00 | BUF Sabres v BOS Bruins | L | 2-3 |
| NHL | 2019/01/06 00:00 | BUF Sabres v BOS Bruins | L | 1-2 |
| NHL | 2018/12/30 00:00 | BOS Bruins v BUF Sabres | L | 3-2 |
| NHL | 2018/12/16 22:00 | BUF Sabres v BOS Bruins | W | 4-2 |
| NHL | 2018/10/04 23:00 | BOS Bruins v BUF Sabres | L | 4-0 |
| NHL | 2018/02/25 22:00 | BOS Bruins v BUF Sabres | W | 1-4 |
| NHL | 2018/02/11 00:00 | BUF Sabres v BOS Bruins | W | 4-2 |
| NHL | 2017/12/20 00:30 | BOS Bruins v BUF Sabres | L | 3-0 |
| NHL | 2017/10/21 23:00 | BUF Sabres v BOS Bruins | W | 5-4 |
| NHL | 2016/12/31 18:00 | BUF Sabres v BOS Bruins | L | 1-3 |
| NHL | 2016/12/30 00:00 | BOS Bruins v BUF Sabres | L | 4-2 |
| NHL | 2016/12/03 18:00 | BOS Bruins v BUF Sabres | L | 2-1 |
| NHL | 2016/11/08 00:00 | BUF Sabres v BOS Bruins | L | 0-4 |