| US Open | 08/27 15:00 | 23 | [127] Gilles Müller v Lorenzo Sonego [121] | 6-7,7-6,7-5,6-7,2-6 | |
| Challenger - Vancouver | 08/15 19:00 | 26 | [117] Gilles Müller v Yannick Maden [131] | 4-6,6-7 | |
| Challenger - Vancouver | 08/14 19:35 | 25 | [117] Gilles Müller v Christopher Eubanks [205] | 6-4,4-6,6-3 | |
| ATP - Los Cabos | 08/01 03:00 | 25 | [104] Gilles Müller v Quentin Halys [150] | 4-6,4-6 | |
| ATP - Newport | 07/18 17:00 | 26 | [124] Marcel Granollers v Gilles Müller [95] | 7-5,7-6 | |
| ATP - Newport | 07/17 16:25 | 25 | [96] Marcos Baghdatis v Gilles Müller [95] | 6-7,3-6 | |
| Wimbledon | 07/04 16:00 | 24 | [27] Philipp Kohlschreiber v Gilles Müller [60] | 7-6,7-6,7-6 | |
| Wimbledon | 07/02 10:30 | 23 | [60] Gilles Müller v Michael Mmoh [119] | 7-5,4-6,7-6,3-6,6-1 | |
| ATP - Eastbourne | 06/25 11:55 | 25 | [46] Gilles Müller v John Millman [63] | 7-6,3-6,2-6 | |
| ATP - Queens | 06/20 15:25 | 26 | [6] Marin Cilic v Gilles Müller [46] | 4-6,6-3,6-3 | |
| ATP - Queens | 06/18 11:00 | 25 | [23] Denis Shapovalov v Gilles Müller [46] | 6-7,6-7 | |
| ATP - Hertogenbosch | 06/13 13:25 | 26 | [32] Gilles Müller v Matthew Ebden [69] | 3-6,5-7 | |
| French Open | 05/28 09:00 | 23 | [160] Ernests Gulbis v Gilles Müller [34] | 2-6,6-4,6-4,6-3 | |
| ATP - Rom | 05/14 09:00 | 24 | [65] Aljaz Bedene v Gilles Müller [35] | 6-4,6-4 | |
| ATP - Estoril | 05/02 17:00 | 26 | [64] Frances Tiafoe v Gilles Müller [28] | 6-4,7-5 | |
| ATP - Monte Carlo | 04/17 16:35 | 25 | [28] Gilles Müller v Alexander Zverev [4] | 6-4,3-6,2-6 | |
| ATP - Monte Carlo | 04/16 13:35 | 24 | [74] Florian Mayer v Gilles Müller [28] | 5-7,4-6 | |
| Davis Cup | 04/08 10:30 | 27 | Gilles Müller v George Tsivadze | Cancelled | |
| Davis Cup | 04/07 13:00 | 27 | Gilles Müller v Zura Tkemaladze | 6-3,6-2 | |
| ATP - Miami | 03/23 21:10 | 24 | [102] Mikhail Youzhny v Gilles Müller [28] | 4-6,6-4,6-2 | |
| ATP - Indian Wells | 03/11 18:00 | 24 | Pierre-Hugues Herbert v Gilles Müller | 6-3,7-5 | |
| ATP - Marseille | 02/22 14:40 | 26 | Gilles Müller v Nicolas Mahut | 6-3,2-6,4-6 | |
| ATP - Marseille | 02/21 13:00 | 25 | Gilles Müller v Sergiy Stakhovsky | 7-5,6-3 | |
| ATP - Marseille | 02/21 12:20 | - | Gilles Müller v Daniil Medvedev | Cancelled | |
| ATP - Rotterdam | 02/13 12:55 | 25 | Daniil Medvedev v Gilles Müller | 6-4,7-6 | |
| ATP - Rotterdam | 02/12 09:00 | 25 | Joao Sousa v Gilles Müller | Cancelled | |
| ATP - Sofia | 02/09 10:00 | 27 | Marius Copil v Gilles Müller | 6-4,6-4 | |
| ATP - Sofia | 02/08 10:00 | 26 | Andreas Seppi v Gilles Müller | 6-4,6-7,6-7 | |
| Australian Open | 01/19 01:35 | 25 | Pablo Carreno-Busta v Gilles Müller | 7-6,4-6,7-5,7-5 | |
| Australian Open | 01/17 00:00 | 24 | Malek Jaziri v Gilles Müller | 5-7,4-6,7-6,6-3,2-6 |