Northwestern 14-47 Illinois 2021-11-27 20:30
Stadion: Memorial Stadium (Champaign, IL) Round: 1
Home Manager: Bret Bielema Away Manager: Pat Fitzgerald
Head to Head
| NCAAF | 2020/12/12 17:00 | Illinois v Northwestern | W | 10-28 |
| NCAAF | 2019/11/30 17:00 | Northwestern v Illinois | W | 29-10 |
| NCAAF | 2018/11/24 20:30 | Illinois v Northwestern | W | 16-24 |
| NCAAF | 2017/11/25 21:00 | Northwestern v Illinois | W | 42-7 |
| NCAAF | 2016/11/26 17:00 | Illinois v Northwestern | W | 21-42 |
| NCAAF | 2015/11/28 20:30 | Illinois v Northwestern | W | 14-24 |
| NCAAF | 2014/11/29 17:00 | Northwestern v Illinois | L | 33-47 |
| NCAAF | 2012/11/24 12:00 | Northwestern v Illinois | W | 50-14 |
Home History
| NCAAF | 2021/11/20 17:00 | Purdue v Northwestern | L | 32-14 |
| NCAAF | 2021/11/13 17:00 | Northwestern v Wisconsin | L | 7-35 |
| NCAAF | 2021/11/06 23:00 | Iowa v Northwestern | L | 17-12 |
| NCAAF | 2021/10/30 19:30 | Minnesota v Northwestern | L | 41-14 |
| NCAAF | 2021/10/23 16:00 | Northwestern v Michigan | L | 7-33 |
| NCAAF | 2021/10/16 16:00 | Rutgers v Northwestern | W | 7-21 |
| NCAAF | 2021/10/02 23:30 | Northwestern v Nebraska | L | 7-56 |
| NCAAF | 2021/09/25 16:00 | Ohio v Northwestern | W | 6-35 |
Away History
| NCAAF | 2021/11/20 19:00 | Illinois v Iowa | L | 23-33 |
| NCAAF | 2021/11/06 16:00 | Illinois v Minnesota | W | 14-6 |
| NCAAF | 2021/10/30 16:00 | Rutgers v Illinois | L | 20-14 |
| NCAAF | 2021/10/23 16:00 | Illinois v Penn State | W | 20-18 |
| NCAAF | 2021/10/09 19:30 | Wisconsin v Illinois | L | 24-0 |
| NCAAF | 2021/10/02 16:00 | Charlotte v Illinois | W | 14-24 |
| NCAAF | 2021/09/25 19:30 | Illinois v Purdue | L | 9-13 |
| NCAAF | 2021/09/18 01:00 | Maryland v Illinois | L | 20-17 |