Stadion: Rice-Totten Stadium Round: 1
Home Manager: Vincent Dancy Away Manager: Willie Simmons
| NCAAF | 2021/10/16 18:00 | Florida A&M v Alabama | W | 35-31 |
| NCAAF | 2021/10/09 22:00 | South Carolina State v Florida A&M | W | 7-30 |
| NCAAF | 2021/10/02 22:00 | Alabama State v Florida A&M | W | 0-28 |
| NCAAF | 2021/09/18 23:00 | Florida A&M v South Florida | L | 17-38 |
| NCAAF | 2021/09/11 22:00 | Florida A&M v Fort Valley State | W | 34-7 |
| NCAAF | 2021/09/05 19:00 | Jackson State v Florida A&M | L | 7-6 |
| NCAAF | 2019/11/23 20:30 | Bethune Cookman v Florida A&M | L | 31-27 |
| NCAAF | 2019/11/16 21:00 | Howard v Florida A&M | W | 7-39 |
| NCAAF | 2021/10/16 20:00 | Alcorn State v Mississippi Valley State | L | 24-12 |
| NCAAF | 2021/10/09 20:00 | Mississippi Valley State v Bethune Cookman | W | 20-14 |
| NCAAF | 2021/10/02 20:00 | North Carolina Central v Mississippi Valley State | W | 16-17 |
| NCAAF | 2021/09/26 19:00 | Southern v Mississippi Valley State | L | 38-25 |
| NCAAF | 2021/09/18 23:00 | Mississippi Valley State v Stephen F. Austin | L | 13-58 |
| NCAAF | 2021/09/03 00:00 | Mississippi Valley State v Murray State | L | 0-35 |
| NCAAF | 2021/04/10 19:00 | Mississippi Valley State v Alabama State | L | 17-42 |
| NCAAF | 2021/04/03 20:00 | Arkansas Pine Bluff v Mississippi Valley State | L | 24-17 |