Stadion: Elliott T. Bowers Stadium Round: 1
Home Manager: K.C. Keeler Away Manager: Eric Morris
| NCAAF | 2021/04/17 16:00 | Sam Houston State v Incarnate Word | L | 42-14 |
| NCAAF | 2019/09/21 23:00 | Incarnate Word v Sam Houston State | L | 6-45 |
| NCAAF FCS | 2018/11/03 19:00 | Sam Houston State v Incarnate Word | W | 26-43 |
| NCAAF | 2017/11/04 18:00 | Sam Houston State v Incarnate Word | L | 57-20 |
| NCAAF | 2021/11/27 20:00 | Stephen F. Austin v Incarnate Word | W | 28-35 |
| NCAAF | 2021/11/20 20:00 | Incarnate Word v Houston Christian | W | 55-14 |
| NCAAF | 2021/11/13 21:00 | Incarnate Word v Nicholls State | W | 27-23 |
| NCAAF | 2021/11/06 19:00 | SE Louisiana v Incarnate Word | W | 52-55 |
| NCAAF | 2021/10/30 20:00 | Houston Christian v Incarnate Word | W | 21-49 |
| NCAAF | 2021/10/23 17:00 | Incarnate Word v McNeese State | L | 20-28 |
| NCAAF | 2021/10/16 16:00 | Nicholls State v Incarnate Word | W | 21-38 |
| NCAAF | 2021/10/02 23:00 | Incarnate Word v Northwestern State | W | 38-27 |
| NCAAF | 2021/11/20 19:00 | Sam Houston State v Abilene Christian | W | 35-9 |
| NCAAF | 2021/11/13 18:00 | Eastern Kentucky v Sam Houston State | W | 28-42 |
| NCAAF | 2021/11/06 17:00 | Utah Tech v Sam Houston State | W | 10-59 |
| NCAAF | 2021/10/30 23:00 | Sam Houston State v Tarleton State | W | 45-27 |
| NCAAF | 2021/10/23 19:00 | Jacksonville State v Sam Houston State | W | 7-42 |
| NCAAF | 2021/10/09 19:00 | Lamar v Sam Houston State | W | 7-41 |
| NCAAF | 2021/10/02 21:00 | Sam Houston State v Stephen F. Austin | W | 21-20 |
| NCAAF | 2021/09/25 21:00 | Sam Houston State v Central Arkansas | W | 45-35 |