Stadion: DeGol Field Round: 1
Home Manager: Chris Villarrial Away Manager: Jerry Schmitt
| NCAAF | 2021/10/30 19:00 | St.Francis (PA) v Duquesne | L | 17-10 |
| NCAAF | 2019/11/02 16:00 | St.Francis (PA) v Duquesne | W | 21-30 |
| NCAAF | 2018/10/20 16:00 | St.Francis (PA) v Duquesne | W | 20-27 |
| NCAAF | 2017/10/21 16:00 | Duquesne v St.Francis (PA) | W | 24-7 |
| NCAAF | 2022/11/05 16:00 | Sacred Heart v Duquesne | W | 28-35 |
| NCAAF | 2022/10/29 16:00 | LIU Brooklyn v Duquesne | L | 50-48 |
| NCAAF | 2022/10/22 16:00 | Duquesne v Central Connecticut | W | 30-6 |
| NCAAF | 2022/10/08 17:00 | Merrimack v Duquesne | L | 28-21 |
| NCAAF | 2022/10/01 16:00 | Duquesne v Stonehill | L | 20-24 |
| NCAAF | 2022/09/18 04:00 | Duquesne v Hawaii | L | 14-24 |
| NCAAF | 2022/09/10 16:00 | Duquesne v Thomas More Saints | W | 34-14 |
| NCAAF | 2022/09/03 18:00 | Duquesne v Youngstown State | L | 14-31 |
| NCAAF | 2022/11/05 16:30 | St.Francis (PA) v Georgetown | W | 38-24 |
| NCAAF | 2022/10/29 16:00 | St.Francis (PA) v Sacred Heart | W | 44-14 |
| NCAAF | 2022/10/22 17:00 | Stonehill v St.Francis (PA) | W | 13-17 |
| NCAAF | 2022/10/15 17:00 | St.Francis (PA) v LIU Brooklyn | W | 57-7 |
| NCAAF | 2022/10/01 16:00 | Central Connecticut v St.Francis (PA) | W | 13-39 |
| NCAAF | 2022/09/24 18:00 | St.Francis (PA) v Norfolk State | W | 45-26 |
| NCAAF | 2022/09/17 20:00 | St.Francis (PA) v Wagner | W | 27-7 |
| NCAAF | 2022/09/10 21:30 | St.Francis (PA) v Richmond | L | 21-31 |